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CHTP - Chelsea Therapeutics International

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  1. [verwijderd] 14 december 2011 22:12
    Na uuuuurrren stilstand op 4.98 tot 5.01 plots in de laatste tien minuten een race naar 5.10 met een meer dan gemiddelde sluitpost.
    Voorkennis?
    Morgen bericht Fibro?
    Zo niet.....we wachten (langzamerhand wat minder) geduldig af.
    Het echte geweld mogen we in februari/maart a.s. tegemoetzien.
  2. [verwijderd] 22 december 2011 15:14
    Simpelweg een goed bericht. Zoals gebruikelijk zal op een goed fase-2-bericht de koers even iets aantrekken en wellicht weer wat terugvallen. Voor het echte werk wachten we op de uitslag van het advisory panel in februari a.s. resp. de goedkeuring van de FDA in maart a.s. voor Northera. Die episodes zie ik met groot vertrouwen tegemoet.
  3. [verwijderd] 22 december 2011 21:13
    Het is niet een goed bericht, maar een zeer fraai bericht. Denk eens even na: ze hebben Carbidopa niet nodig. Dus geen ander, die mee moet doen.
    En we weten al langer dan vandaag, dat droxidopa er zeer gunstig uitkomt wat betreft bijwerkingen.
    Volledige zekerheid heb je niet in biotech, maar ik acht Chelsea één van de grootste kanshebbers op succes.
    En dus is de koersreactie van vandaag weer veel te gering.
    Hierbij zij opgemerkt, dat voor het middel tegen Fibromyalgie nog een weg van minstens drie jaar te gaan is.
    Maar straks in februari/maart krijgen we het keuringsresultaat van Northera voor een deel der PD-patienten met een flinke kans op succes.
    Gewoon geduldig blijven!

    Goede feestdagen allemaal!!
  4. ludwig mack 3 januari 2012 13:57
    Chelsea Therapeutics Announces FDA Advisory Committee Meeting Date for Review of NORTHERA(TM) NDA for the Treatment of Symptomatic NOH
    Cardiovascular and Renal Drugs Advisory Committee Meeting Scheduled for February 23, 2012

    CHARLOTTE, N.C., Jan. 3, 2012 (GLOBE NEWSWIRE) -- Chelsea Therapeutics International, Ltd. (Nasdaq:CHTP) announced that the U.S. Food and Drug Administration (FDA) has scheduled a meeting of the Cardiovascular and Renal Drugs Advisory Committee on February 23, 2012 to review the New Drug Application (NDA) for NORTHERA™ (droxidopa). Northera is an orally active synthetic precursor of norepinephrine, for the treatment of symptomatic neurogenic orthostatic hypotension (NOH) in patients with primary autonomic failure (Parkinson's disease, multiple system atrophy and pure autonomic failure), dopamine beta hydroxylase deficiency and non-diabetic autonomic neuropathy.

    The Northera NDA along with a request for Priority Review was submitted to the FDA on September 28th 2011. FDA previously granted Chelsea's request for Priority Review, and, under the Prescription Drug User Fee Act (PDUFA), FDA's goal is to review and act on the NDA by March 28, 2012. FDA grants Priority Review to drugs offering major advances in treatment, or providing a treatment where no adequate therapy exists.

    The Cardiovascular and Renal Drugs Advisory Committee is an independent panel of experts that reviews and evaluates available data concerning the safety and effectiveness of products for use in the treatment of cardiovascular and renal disorders and makes appropriate recommendations to the FDA.

    Background materials, when available, or changes to the Advisory Committee meetings calendar can be found on the FDA website at www.fda.gov/AdvisoryCommittees/Calend...

  5. ludwig mack 5 januari 2012 23:03
    persbericht:

    Chelsea Therapeutics Announces Proposed Public Offering of Common Stock

    CHARLOTTE, N.C., Jan. 5, 2012 (GLOBE NEWSWIRE) -- Chelsea Therapeutics International, Ltd. (Nasdaq:CHTP) announced today its intention to offer, subject to market and other conditions, $20.0 million of its common stock in an underwritten public offering pursuant to its existing shelf registration statement. The company also intends to grant to the underwriters a 30-day option to purchase up to an additional 15% of the shares of common stock sold in the public offering to cover over-allotments, if any.

    Leerink Swann LLC is acting as the sole book-running manager for the offering. Needham & Company, LLC and Roth Capital Partners, LLC are acting as the co-managers of the offering.

    The securities described above are being offered by Chelsea pursuant to a registration statement previously filed and declared effective by the Securities and Exchange Commission. This press release does not constitute an offer to sell or a solicitation of an offer to buy the securities in this offering. The offering may be made only by means of a prospectus, copies of which may be obtained, when available, from Leerink Swann LLC, Attention: Syndicate Prospectus Department, One Federal Street, 37th Floor, Boston, Massachusetts 02110, by telephone at 617-918-4814, or by facsimile at 617-918-4914.

  6. ludwig mack 6 januari 2012 14:55
    en nog een:

    Chelsea Therapeutics Prices Public Offering of Common Stock

    CHARLOTTE, N.C., Jan. 6, 2012 (GLOBE NEWSWIRE) -- Chelsea Therapeutics International, Ltd. (Nasdaq:CHTP) announced today that it has priced an underwritten public offering of 4,338,500 shares of its common stock at a price of $4.75 per share. Net proceeds after underwriting discounts and commissions and expenses will be approximately $19.2 million. The company also has granted the underwriters a 30-day option to purchase up to an additional 650,775 shares to cover over-allotments, if any, which would result in additional net proceeds of approximately $2.9 million, if exercised in full. The offering is expected to close on or about January 11, 2012, subject to satisfaction of customary closing conditions.

    Leerink Swann LLC is acting as the sole book-running manager for the offering. Needham & Company, LLC and Roth Capital Partners, LLC are acting as the co-managers of the offering.

    The securities described above are being offered by Chelsea pursuant to registration statements on Form S-3 previously filed and declared effective by the Securities and Exchange Commission. This press release does not constitute an offer to sell or a solicitation of an offer to buy the securities in this offering. A preliminary prospectus supplement relating to the offering has been filed with the Securities and Exchange Commission, and a final prospectus supplement relating to the offering will be filed with the Securities and Exchange Commission. The offering may be made only by means of a prospectus, and copies of the final prospectus supplement and accompanying prospectus may be obtained, when available, from Leerink Swann LLC, Attention: Syndicate Prospectus Department, One Federal Street, 37th Floor, Boston, Massachusetts 02110, by telephone at 617-918-4814, or by facsimile at 617-918-4914.

  7. [verwijderd] 6 januari 2012 15:40
    We hadden het kunnen weten, op 30 december dit bericht:
    -----------------------------------------------------------------------
    12.30.11 | Frank Vinluan
    Chelsea Therapeutics to raise $19.7M for new drug launch and drug pipeline

    Chelsea Therapeutics (NASDAQ:CHTP) is preparing for the launch of its first product — a drug for Parkinson’s disease patients — and the company plans to arm itself with nearly $20 million to do it.

    Chelsea aims to raise up to $19.7 million through a stock offering of more than 65 million shares, according to an updated prospectus the Charlotte, North Carolina company filed with regulators. Net proceeds from the offering would fund the company’s droxidopa program.

    AdvertisementDroxidopa is a drug candidate that Chelsea aims to market under the name Northera. It was studied as a treatment for dizziness and fainting experienced by patients with Parkinson’s disease. Now under priority review by the U.S. Food and Drug Administration, Northera could receive an approval decision by March 28. Droxidopa is also being studied in other indications; the compound is in phase 2 clinical trials as a fibromyalgia treatment. Chelsea recently reported positive results from the study, which evaluated potential therapeutic dosing of droxidopa by itself and in combination with Parkinson’s drug carbidopa.

    In addition to supporting the droxidopa program, Chelsea said proceeds from the offering will fund the company’s study of the compound CH-4501, an experimental rheumatoid arthritis treatment currently in phase 2 clinical trials.

    Chelsea at the beginning of the year filed a shelf registration to raise up to $60 million, money that would be used to support its drug pipeline. The current offering follows a February stock sale that net Chelsea $37.8 million. Chelsea is conducting the current offering in a different manner. The sale will be an “at-the-market” or ATM offering conducted by Cantor Fitzgerald. In an ATM, a company’s stock is sold over an extended period of time rather than all at once at a fixed price. ATMs give a company more flexibility in how and when they raise money.

    --------------------------------------------------------------------------
    Alleen dacht ik toen ik het las: Dat Kan Niet Waar Zijn, 65 mln aandelen voor $ 19,7 mio, 30 cent per stuk.
  8. ludwig mack 6 januari 2012 16:19
    Last Trade: 4.95
    Trade Time: 10:01AM EST
    Change: Down 0.35 (6.60%)
    Prev Close: 5.30
    Open: 4.93
    Bid: 4.95 x 100
    Ask: 4.95 x 100
    1y Target Est: 11.33
    Day's Range: 4.86 - 5.03
    52wk Range: 3.25 - 8.20
    Volume: 818,859
    Avg Vol (3m): 350,551
    Market Cap: 306.14M
    P/E (ttm): N/A
    EPS (ttm): -0.89
    Div & Yield: N/A (N/A)
  9. ludwig mack 6 januari 2012 16:22
    quote:

    tophound schreef op 6 januari 2012 15:46:

    Waarom geen claimemissie ?
    onzekerheid; zo lang de basis nog niet goed gelegd is, zijn huidige aandeelhouders niet zo geneigd dat ze altijd willen intekenen, zo vermoed ik.
    gr
  10. ludwig mack 6 januari 2012 16:27
    quote:

    tophound schreef op 6 januari 2012 15:40:

    We hadden het kunnen weten, op 30 december dit bericht:
    -----------------------------------------------------------------------
    12.30.11 | Frank Vinluan
    Chelsea Therapeutics to raise $19.7M for new drug launch and drug pipeline

    Chelsea Therapeutics (NASDAQ:CHTP) is preparing for the launch of its first product — a drug for Parkinson’s disease patients — and the company plans to arm itself with nearly $20 million to do it.

    Chelsea aims to raise up to $19.7 million through a stock offering of more than 65 million shares, according to an updated prospectus the Charlotte, North Carolina company filed with regulators. Net proceeds from the offering would fund the company’s droxidopa program.

    AdvertisementDroxidopa is a drug candidate that Chelsea aims to market under the name Northera. It was studied as a treatment for dizziness and fainting experienced by patients with Parkinson’s disease. Now under priority review by the U.S. Food and Drug Administration, Northera could receive an approval decision by March 28. Droxidopa is also being studied in other indications; the compound is in phase 2 clinical trials as a fibromyalgia treatment. Chelsea recently reported positive results from the study, which evaluated potential therapeutic dosing of droxidopa by itself and in combination with Parkinson’s drug carbidopa.

    In addition to supporting the droxidopa program, Chelsea said proceeds from the offering will fund the company’s study of the compound CH-4501, an experimental rheumatoid arthritis treatment currently in phase 2 clinical trials.

    Chelsea at the beginning of the year filed a shelf registration to raise up to $60 million, money that would be used to support its drug pipeline. The current offering follows a February stock sale that net Chelsea $37.8 million. Chelsea is conducting the current offering in a different manner. The sale will be an “at-the-market” or ATM offering conducted by Cantor Fitzgerald. In an ATM, a company’s stock is sold over an extended period of time rather than all at once at a fixed price. ATMs give a company more flexibility in how and when they raise money.

    --------------------------------------------------------------------------
    Alleen dacht ik toen ik het las: Dat Kan Niet Waar Zijn, 65 mln aandelen voor $ 19,7 mio, 30 cent per stuk.
    ik kan het niet terugvinden; waar stond het?
    gr
  11. ludwig mack 6 januari 2012 23:20
    quote:

    tophound schreef op 6 januari 2012 19:05:

    www.medcitynews.com/2011/12/chelsea-t...

    Of via Google Finance: nieuwsberichten betr. CHTP.
    jammer dat je het niet plaatste, want de prijs wordt aangegeven in de prospectus, die je kunt doorklikken; dan had ik verkocht en vandaag weer met meer ingekocht ......

    zie de tekst en kijk naar de prijs (die werd aangenomen, maar kon gewijzigd worden naar verloop van de koers natuurlijk de laatste weken).

    We will pay Cantor commissions for its services in acting as agent in the sale of common stock. Cantor will be entitled to compensation at a fixed commission rate ranging between 3.0% and 5.0% of the gross sales price per share sold. Assuming the sale of shares of common stock having aggregate gross sales proceeds of $19,750,000 at an assumed offering price of $5.17 per share, which was the closing sales price of our common stock as reported on the NASDAQ Capital Market on December 28, 2011, we estimate that the total expenses for the offering, excluding compensation payable to Cantor under the terms of the sales agreement, will be approximately $120,000, which includes certain expense reimbursements payable to Cantor.

    wat ik niet begrijp, zie :

    Chelsea aims to raise up to $19.7 million through a stock offering of more than 65 million shares, according to an updated prospectus the Charlotte, North Carolina company filed with regulators. Net proceeds from the offering would fund the company’s droxidopa program.

    einde citaat uit dat p.b.,

    is dat het gedeponeerd is en wij van niets wisten; zie de woorden filen.

    tja. ik hou van l.t. maar had met deze info wel even de makelaar zijn winst gegeven door verkoop en koop.

    laten we het rusten en het beste er van hopen.

    vandaag eagon, iets totaal anders ;-), uitgebreid en ik hoop op overname ....

    gr
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