SkySpam1 schreef:
Posted by: DewDiligence
In reply to: None Date:8/17/2006 9:59:53 PM
Post #of 521
GTC was on Boston TV today. The video clip,
which can be accessed from the link below,
comes across as more intelligent than the
written report presented here.
www.thebostonchannel.com/asseenon5/96...>>
Saving Lives...With Goats?
August 17, 2006
BOSTON -- Farmyard animals could be saving the lives of humans, if local research proves successful.
NewsCenter 5's Heather Unruh reported that hybrid goats being raised on a Charlton farm could revolutionize the way doctors treat patients.
The drug ATryn, the world's first medicine produced from the milk of hybrid goats, has been approved in Europe to treat people with a rare blood disorder.
People who need ATryn are prone to blood clots and often are taking blood thinners to decrease their risks of heart attacks and strokes, researchers said. But patients must stop taking those medications before having surgery or childbirth to decrease the chance of excess bleeding. That, researchers said, is where ATryn comes in.
"They need their anti-thrombin levels brought up to normal levels in order to go safely through the procedure," said Geoffrey Cox, of GTC Biotherapeutics.
To make ATryn, veterinarians inject goat embryos with DNA. The goats produce milk that has special blood clotting agents. Research showed that these agents are more efficient in producing blood-clotting agents than the traditional treatment, a transfusion of human blood plasma. [This is an awkward way of saying that GTC can produce more antithrombin per unit cost than plasma fractionation companies.]
"One animal produces anti-thrombin compared to 90,000 blood donations," Cox said.
The hybrid goats look and act like typical goats. The only difference, GTC researchers said, is how they are raised.
"The animal food is very clean. The animals are routinely sampled for various viruses. They are carrying a foreign piece of DNA, so, from a physiological standpoint, yes they are producing a human protein. But from a vet standpoint, they are normal everyday mischievous goats," said Michael Schofield, of GTC Biotherapeutics.
ATryn is undergoing clinical trials in the U.S., and could be approved by the Food and Drug Administration next year. [Actually, approval in 2007 is almost impossible; 2008 is much more likely.] GTC is looking at whether ATryn could be used for other conditions, including rheumatoid arthritis, HIV and cancer. [LOL—this is not even close! What they meant was that the technology behind ATryn can be used to produce drugs for manifold medical conditions. The statement is made correctly on the video clip.]
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