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HEB - HEMISPHERX BIOPHARMA INC (US, AMEX)

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  1. [verwijderd] 16 maart 2006 15:52
    6,5 % hoger ....

    New Research From Hemispherx Biopharma Leverages Recent Studies to Identify Factors in Breakdown of Immune System; May Help Prevent Spread of Avian Flu

    PHILADELPHIA--(BUSINESS WIRE)--March 16, 2006--Hemispherx Biopharma, Inc.:

    -- Results to be Presented at the VIII International Symposium on
    Respiratory Viral Infections March 16-19 in Hawaii

    -- Japanese Researchers Initiate Primate Studies With
    Co-administration of Hemispherx Biopharma's Ampligen and H5N1
    Vaccine

    The results of new studies to be presented at the VIII International Symposium on Respiratory Viral Infections on March 16-19 represent a major step forward in leveraging research that identifies the gene that is believed to have caused the immune system to shut down and led to the devastating Spanish flu epidemic of 1918, which is estimated to have killed 100 million people. These studies have critical implications because some researchers believe the current spread of the H5N1, or avian flu, virus may have similar underlying causes. The findings, to be presented by Dr. William Mitchell, Professor of Pathology at Vanderbilt University and a member of the Board of Directors of Hemispherx Biopharma, provide further evidence that Hemispherx Biopharma's Alferon LDO (Low-Dose Oral), a new delivery form of an anti-viral with prior regulatory approval for a category of sexually transmitted diseases, has tremendous potential in resisting the spread of avian flu by stimulating genes that induce the production of immune compounds that are key building blocks in the body's defense system.

    Researchers in this area have recently focused on TNF, a naturally occurring immune substance (or "lymphokine") as the instigator of the massive tissue damage to lung cells. The new research included analysis of avian flu virus specimens recently recovered in the frozen arctic tundra from victims of the 1918 avian flu epidemic. These studies suggest that the interferon system, the body's primary line of defense, broke down first, leading to the aberrant and ultimately self-destructive release of TNF.

    In recent healthy human volunteer tests conducted in Hong Kong and Philadelphia, patients were given graded doses of Alferon LDO for two minutes' exposure. Blood samples were then taken to determine which components of the immune system had been activated. It was found that the interferon gene activity normally suppressed or killed by the virus were instead enhanced several times over. By contrast, the TNF gene battery normally enhanced by viral infection was instead sharply suppressed by the brief Alferon LDO exposure.

    "These new studies are highly significant to our understanding of how the body reacts to virus attacks, a critical component in building adequate defenses against the spread of avian flu," said Dr. William Mitchell. "We believe that taken collectively, the latest findings represent tremendous progress in this critical area."

    Dr. Mitchell will also be presenting ongoing findings from trials on The TLR3 Agonist, Poly I: Poly C12U, Provides Nasal Adjuvant Activity to a Vaccine Directed Against Highly Pathogenic H5N1 Avian Influenza Virus and Synerginistic Inhibition of Avian Influenza Virus (H5N1) by PolyI: Poly C12 U Combined with Oseltamivir or Zanamivir. (All three trials were recently presented at the ASM Biodefense Conference.)

    Dr. Mitchell will announce that the co-administration of Hemispherx Biopharma's experimental immunotherapeutic Ampligen, a specifically configured double-stranded RNA, may help enable substantial reductions in an H5N1 vaccine dose, as well as provide cross-protection against mutated strains of the H5N1 virus. These results come from a conclusive mouse study conducted in collaboration with the National Institute of Infectious Diseases in Japan. In collaboration with Hemispherx Biopharma, the Institute has initiated the next phase of studies with primates.

    Finally, additional research to be presented suggests the effectiveness of Tamiflu and Relenza, the only two drugs formally recognized for combating bird flu, can be boosted up to 100 times. Lab studies reveal that 50 to 100 times less Tamiflu may be used in conjunction with Ampligen to achieve full inhibition with no multiplication of the virus, and no host cell damage.

    "The latest research offers further evidence that we are on the right path to identifying the factors that cause the immune system to break down, which has grave implications in the event of a pandemic," said Dr. William A. Carter, M.D., Chairman and CEO of Hemispherx Biopharma. "We're also encouraged that our experimental immunotherapeutics Ampligen and Alferon offer tremendous potential against the global spread of the H5N1 virus."

  2. [verwijderd] 16 maart 2006 18:45
    nu al + 11,5 %!

    Japanese Researchers Initiate Primate Studies With Co-administration of Hemispherx Biopharma's Ampligen and H5N1 Vaccine

    Het schijnt dat Ampligen de werkzaamheid van diverse vogelgriep vaccins met 100 maal kan vergroten. Er zijn al geruchten dat Roche (Tamiflu) testen wil gaan doen met Ampligen (Heb).

    Als dit zo is, dan gaat de koers skyhigh!
  3. [verwijderd] 20 maart 2006 14:40
    HEB gaat knallen vandaag.
    Er zijn de afgelopen dagen een paar erg goede artikelen verschenen en de verwachting is dat ie snel richting 5 euro kan oplopen.

    yahoo.smartmoney.com/aheadofthecurve/...

    en

    HEB is mentioned in Monday's Investor's Business daily on page A8 - Health and Medicine on bird flu battle. It mentioned Alferon and HPV and cronic fatigue syndrome. In adition to bird flu, it mentioned that Ampligen may also work for seasonal flu, which kills 36,000 annually.

    Ze hebben natuurlijk een potentiele goudmijn in handen met hun Ampligen en Alferon LDO.

    Succes!
  4. [verwijderd] 20 maart 2006 22:06
    Ik wilde wel, maar geen cash!

    Zit in GIGM/GNBT/TMTA en alles omhoog zonder reden om te verkopen...
    Er gaat te veel goed vandaag, hahaha.

    Maar mooi aandeel!
  5. [verwijderd] 20 maart 2006 22:11
    Nou ja, ik heb er ook maar 1k, dus dat schiet nog niet op. Er is zoveel lekkers op de markt dat ik maar van alles wat heb genomen.
    Na het debacle met GTCB moet ik toch weer het een en ander goed zien te maken.
    Zit momenteel in GTCB, GNBT, HEB, INSM, LOUD, PPHM, Sopheon, Begemann, Pharming, Isotis, dus er zit altijd wel iets tussen dat het goed doet ...

    Sopheon zal wel een leuke worden binnenkort.

    In ieder geval allemaal succes en doe je eigen DD, zoals ze in Amerika zeggen.

    Pieter
  6. [verwijderd] 20 maart 2006 22:15
    Het GTCB debacle heb ik gelukkig gemist, maar dat werd al 'goedgemaakt' door INSM. Alhoewel, dat aandeel komt er wel!

    HEB ziet er goed uit, zowel fundamenteel als technisch.

    Kijken of GNBT nog wat meer oplevert, anders dit maar proberen!
  7. [verwijderd] 20 maart 2006 22:35
    quote:

    laroot schreef:

    Zit er niemand hier meer in HEB?
    Terwijl er gouden tijden aankomen ...
    Ieder geval vandaag een plus van 13% op 3,87!

    Succes
    yep heb nog steeds mijn stukken HEB :)) lekkere dag vandaag
  8. [verwijderd] 4 april 2006 16:36
    De koers van HEB stort nu verder in elkaar.($3,12) Ik begrijp dat er fouten zijn gemaakt met de filing, klinkt nogal amateuristisch. Ik ga mijn verlies nemen, of heeft iemand nog iets ten faveure te melden ?
    Leo S
  9. [verwijderd] 4 april 2006 16:54
    Is daar een PB van gekomen? Heb je daar dan een link van ik kan het niet vinden.

    Groeten.

    PS Is het zo erg dat het bedrijf ter ziele gaat dat je je verlies gaat nemen?
  10. [verwijderd] 4 april 2006 17:24
    Ja is niet echt professioneel, maar om daarom je verlies te nemen. Heb je een korte termijn visie op HEB? Is wel zo dat alle griep aandelen aan het dalen zijn. Maar moet het voor jezelf uitmaken natuurlijk. Succes!

    Groeten

    PS Ik heb zelf geen HEB.
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Aalberts 466 7.141
AB InBev 2 5.541
Abionyx Pharma 2 29
Ablynx 43 13.356
ABN AMRO 1.582 52.331
ABO-Group 1 25
Acacia Pharma 9 24.692
Accell Group 151 4.132
Accentis 2 267
Accsys Technologies 23 10.909
ACCSYS TECHNOLOGIES PLC 218 11.686
Ackermans & van Haaren 1 193
Adecco 1 1
ADMA Biologics 1 34
Adomos 1 126
AdUX 2 457
Adyen 14 17.872
Aedifica 3 927
Aegon 3.258 323.135
AFC Ajax 538 7.092
Affimed NV 2 6.305
ageas 5.844 109.907
Agfa-Gevaert 14 2.070
Ahold 3.538 74.353
Air France - KLM 1.025 35.304
AIRBUS 1 12
Airspray 511 1.258
Akka Technologies 1 18
AkzoNobel 467 13.056
Alfen 16 25.377
Allfunds Group 4 1.520
Almunda Professionals (vh Novisource) 651 4.251
Alpha Pro Tech 1 17
Alphabet Inc. 1 426
Altice 106 51.198
Alumexx ((Voorheen Phelix (voorheen Inverko)) 8.486 114.826
AM 228 684
Amarin Corporation 1 133
Amerikaanse aandelen 3.837 244.134
AMG 972 134.579
AMS 3 73
Amsterdam Commodities 305 6.747
AMT Holding 199 7.047
Anavex Life Sciences Corp 2 500
Antonov 22.632 153.605
Aperam 92 15.089
Apollo Alternative Assets 1 17
Apple 5 386
Arcadis 252 8.808
Arcelor Mittal 2.035 321.037
Archos 1 1
Arcona Property Fund 1 287
arGEN-X 17 10.362
Aroundtown SA 1 221
Arrowhead Research 5 9.751
Ascencio 1 28
ASIT biotech 2 697
ASMI 4.108 39.666
ASML 1.766 110.961
ASR Nederland 21 4.517
ATAI Life Sciences 1 7
Atenor Group 1 522
Athlon Group 121 176
Atrium European Real Estate 2 199
Auplata 1 55
Avantium 32 14.216
Axsome Therapeutics 1 177
Azelis Group 1 67
Azerion 7 3.449